ترجمه پاراگراف The effect was significant after con- trolling ...

The effect was significant after con-
trolling for pre-PDMP declines associated with (1) the introduction
of tamper-resistant oxycodone HC1 controlled release tablets to
the market, (2) law enforcement crackdown on pill mills, which
were popular for their oxycodone-alprazolam “cocktails”, and (3)
the tightened rules and regulations around controlled substance
prescribing introduced by House Bill 7095