ترجمه متن تخصصی Background: Total Knee Replacement (TKR) surgery is being...

Background: Total Knee Replacement (TKR) surgery is being utilised in a younger, more active population with 

greater functional expectations. Understanding whether patient-perceived measures of function reflect objective 

biomechanical measures is critical in understanding whether functional limitations can be adequately captured 

within a clinical setting. 

Research Question: Do changes in objective gait biomechanics measures reflect patient-reported outcome mea- 

sures at approximately 12 months following TKR surgery? 

Methods: Three-dimensional gait analysis was performed on 41 patients with OA who were scheduled for TKR 

surgery, 22 of which have returned for a (9—24 month) follow-up assessment. Principal Component Analysis was 

used to define features of variation between OA subjects and an additional 31 non-pathological control subjects. 

These were used to train the Cardiff Classifier, an objective classification technique, and subsequently quantify 

changes following TKR surgery, Patient-perceived changes were also assessed using the Oxford Knee Score 

(ORS), Knee Outcome Survey (KOS), and Pain Audit Collection System scores (PACS). Pearson and Spearman 

correlation coefficients were calculated to establish the relationship between changes in objectively-measured 

and perceived outcome. 

Results: Objective measures of biomechanical change were strongly correlated to changes in OKS(r=- 0.695, 

p < 0.001) and p < 0.001) assessed outcomes. Pain (PACS) was only related to biomechanical 

function post-operatively -.623, p = 0.003). 

Significance: In this biomechanics study, the relationship between changes in objective function and patient- 

reported measures pre to post TKR surgery is stronger than in studies which did not include biomechanics 

metrics. Quality of movement may hold more significance for a patient's perception of improvement than 

functional measures which consider only the time taken or distance travelled during functional activities.