دیگه باهات کاری ندارم.
دیگه کارم باهات تموم شده و هرگز سراغی ازت نخواهم گرفت
دیگه باهات کاری ندارم
از دستت کلافه شدم
دیگه کارم باهات تمومه.
In general it's used to stress that the speaker doesn't wish to keep any relation with the person.
I'm tired of you. You never listen to me. Im disappointed you. And I've lost faith in you.
I don't want to deal with you anymore.